Roberto A. Ribas Zunino
Photo of Roberto A. Ribas Zunino

Metabolism · Immunology · Spatial omics · AI

Roberto A. Ribas ZuninoI publish as Roberto A. Ribas.

I study metabolism: how cells and tissues use and rewire their fuel. So far that has meant cancer, the brain, and rare metabolic disease; next I want to bring it to immunology: how immune cells’ metabolism drives immune-mediated diseases like Crohn’s and ulcerative colitis, uveitis, and Graves’ disease, so we can find better treatments and, one day, cures. My tools have been mass spectrometry imaging and AI, mapping metabolites, lipids, glycogen, and glycans where they sit in tissue.

At the University of Florida I helped build the Center for Advanced Spatial Biomolecule Research, starting as a lab technician and becoming its lead center scientist, with 250+ projects coordinated for labs around the world. I’ve also worked in cGMP quality control and in patient care.

Where I’m headed: foundational, high-risk ideas at the edges of what biology can do, where one result could help millions of people. Mass spectrometry got me here, but it isn’t the destination: next I want to learn new fields and new tools, keep growing, and follow the most important problems wherever they lead.

  • Open to research roles
  • Academia or industry
  • Available to start immediately
  • English / Spanish
Where fields meetEach field is a line. My work sits where they cross: spatial glycomics, MetaVision3D and a core facility are done; immune-mediated disease (Crohn’s, IBD, uveitis, Graves’), measurement at scale and biology at the extremes are next.Multi-enzyme spatial glycomicsMetaVision3DRunning a core facilityImmune-mediated diseaseMeasurement at scaleBiology at the extremes
  • Biology
  • Chemistry & mass spec
  • Computation & AI
  • Immunology & medicine
  • Engineering
Discoveries happen where fields meet.
19publications & preprints
3first / co-first author papers
250+core-facility projects coordinated
6,000+biological samples tracked

03

Experience

Feb 2023 – Mar 2026
Gainesville, FL

University of Florida College of Medicine

Sun, Gentry & Vander Kooi Laboratories, Dept. of Biochemistry & Molecular Biology

Laboratory Technician (Feb 2023 – Mar 2026) · Lead Center Scientist & Team Lead, CASBR (Jul 2023 – Mar 2026) · Research Assistant (Aug 2025 – Mar 2026)

  • Studied metabolism across cancer, neurodegeneration and rare metabolic disease with MALDI timsTOF mass spectrometry imaging: spatial metabolomics, lipidomics and glycomics (glycogen and N-glycans), on fresh-frozen and FFPE tissue.
  • Operated and maintained the Bruker timsTOF and coordinated service visits with Bruker and HTX.
  • First author on methods for mass spectrometry imaging of the cochlea (J Am Soc Mass Spectrom, 2026) and of the glycome (J Vis Exp, 2025); one of four co-first authors on MetaVision3D, an AI-driven 3D map of the brain metabolome (Nature Metabolism, 2025).
  • Developed Vision (in-house, unpublished), an all-in-one platform combining Sami (Nat Commun) and MetaVision3D (Nat Metab) for analysis, visualization and spatial UMAP clustering of high-dimensional spatial omics data.
  • Coordinated workflows for 250+ CASBR projects, wrote 10+ standardized protocols, and trained and led a team of 8 researchers.
  • Ran day-to-day lab operations: purchasing and spend tracking, vendor quotes, instrument service contracts, material transfer agreements, sample shipping with collaborators worldwide, and tracking for 6,000+ samples.
  • In vivo mouse work under approved protocols: IP, tail-vein and oral-gavage dosing; blood collection; dissection and tissue harvest; behavioral testing; viral-vector lung tumor induction; helped maintain breeding colonies (breeder setup, weaning, Transnetyx genotyping).
  • Generated spatial multiomics data for collaborations with groups worldwide, contributing to 19 publications and preprints.
Apr 2026 – May 2026
Miami, FL

Vivex Biologics

Quality Control Microbiologist I

  • cGMP microbiological testing, environmental monitoring and VITEK 2 identification to ensure raw material and finished product compliance with regulatory specifications in a biologics manufacturing facility.
Apr 2022 – Sep 2023
Gainesville, FL

University of Florida, Dias Laboratory

Undergraduate Researcher, Dept. of Microbiology & Cell Science

  • Applied AI models to integrate host–microbe omics data for disease prediction.
May 2022 – Oct 2023
Gainesville, FL

UF Health

Personal Care Assistant, Cardiovascular & Lung Transplant Unit

  • Patient hygiene, mobility, vital signs and records in a transplant care setting.

04

Hands-on skills

Everything listed is hands-on, not exposure. Ask the chat about anything not on this list and it will tell you honestly whether I have done it.

Mass spectrometry imaging

  • MALDI timsTOF imaging (metabolites, lipids, glycogen, N-glycans)
  • Matrix sublimation & recrystallization (NEDC)
  • Multi-enzyme on-tissue digestion (PNGase F, isoamylase)
  • Fresh-frozen and FFPE tissue
  • 3D spatial reconstruction
  • HPLC

In vivo (mouse)

  • IP, tail-vein and oral-gavage dosing
  • Blood collection
  • Dissection & tissue harvest
  • Behavioral testing
  • Viral-vector lung tumor induction
  • Microwave fixation of rodent brain
  • Helped maintain breeding colonies (breeders, weaning, genotyping)

Tissue & histology

  • Cryosectioning (fresh-frozen)
  • Sectioning of human FFPE tissue
  • Immunohistochemistry
  • Immunofluorescence
  • Histological staining

Cell, micro & quality

  • Mammalian cell culture, aseptic technique
  • Cell counting & viability assays
  • Microbial culture, Gram stain, VITEK 2
  • cGMP, environmental monitoring
  • SOP development
  • BSL-2

Lab operations

  • Purchasing & spend tracking
  • Vendor quotes & service contracts (Bruker, HTX)
  • Material transfer agreements
  • Domestic & international sample shipping
  • Project intake & scheduling for a core facility

Data

  • Python
  • R
  • Power BI
  • GraphPad Prism
  • Excel
  • Machine learning for multiomics integration

05

Selected publications

14 peer-reviewed (3 first or co-first author), 1 accepted in Nature Neuroscience, and 4 preprints.

  1. 2026
    Mass spectrometry-based spatial imaging of the cochlea
    Ribas RA, Tang Q, Caffee SI, … Gentry MS, Sun RC, Vander Kooi CW
    J Am Soc Mass Spectrom 2026;37(5):1187–95 · DOI · PubMed · Case study
  2. 2025
    Spatial molecular imaging of the glycome using mass spectrometry
    Ribas RA, Paolasso FB, Ryan AM, … Gentry MS, Sun RC, Vander Kooi CW
    J Vis Exp 2025;(225):e69154 · DOI · PubMed · Case study
  3. 2025
    AI-driven framework to map the brain metabolome in three dimensions
    Ma X*, Shedlock CJ*, Medina T*, Ribas RA*, … Chen L, Sun RC
    Nat Metab 2025;7(4):842–53 · DOI · PubMed · Case study
  4. 2026
    Hyperglycosylation is a metabolic driver of Alzheimer’s disease
    Hawkinson TR, Liu Z, Ribas RA, … Vander Kooi CW, Gentry MS, Sun RC
    Nat Metab 2026;8(6):1410–25 · DOI · PubMed
  5. 2026
    Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma
    Bernardi F, Torrejon J, Basili I, … Ribas RA, … Taylor MD, Ayrault O
    Cancer Cell 2026;44(2):383–404.e18 · DOI · PubMed
  6. 2025
    Spatial mapping of the brain metabolome lipidome and glycome
    Clarke HA, Ma X, Shedlock CJ, … Ribas RA, … Chen L, Sun RC
    Nat Commun 2025;16(1):4373 · DOI · PubMed
  7. 2025
    Glycogen drives tumour initiation and progression in lung adenocarcinoma
    Clarke HA, Hawkinson TR, Shedlock CJ, Medina T, Ribas RA, … Gentry MS, Sun RC
    Nat Metab 2025;7(5):952–65 · DOI · PubMed

All 19 publications and preprints →

06

Education

  • M.S., Microbiology and Cell Science (Medical Microbiology & Biochemistry)
    University of Florida (online program) · May 2023 – Present
  • B.S., Microbiology and Cell Science; Certificate in AI Fundamentals and Applications
    University of Florida · Aug 2020 – Dec 2022
  • A.A., Biological Sciences, Graduated with Distinction
    Santa Fe College · Aug 2018 – Aug 2020

Teaching, leadership & outreach

  • Co-Director, UF Global Health Case Competition (2023–2024); Case Writer (2022–2023)
  • Undergraduate Teaching Assistant, UF microbiology labs MCB3023L and MCB2000L (2020–2022)
  • Mathematics and Science Tutor, GoStudent (2022–2023)
  • Panelist, UF COM Biochemistry & Molecular Biology: Academic Life After State College (2024)
  • Posters: Winter Conference on Brain Research (2025); UF College of Medicine Research Day (2024, 2025)
  • HTX Imaging Application Note 69: NEDC matrix sublimation and recrystallization (data contributor, 2026)

In the news

Let’s talk

I’m open to research roles in academia and industry, especially where I can learn new fields and keep growing. I’m based in South Florida and happy to relocate. Reach out about research, collaborations or positions; escribe en español si prefieres.

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